SPIRONOLACTONE THERAPY IN HIRSUTISM AND ACNE
1988; Wiley; Volume: 29; Issue: 3 Linguagem: Inglês
10.1111/j.1440-0960.1988.tb00385.x
ISSN1440-0960
Autores Tópico(s)Acne and Rosacea Treatments and Effects
ResumoS ummary Spironolactone has been found to have anti‐androgenic properties and to be useful in the treatment of female hirsulism. Benefits have also been noted in the treatment of mature age onset or persistent acne in females. The mechanism of action of this drug is mainly via a peripheral anti‐androgenic effect but it may also result in decreased androgen production. The results of a number of clinical studies are discussed with particular reference to the side effects of spironolactone. Guidelines for treatment of hirsutism and female mature age acne are given.
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