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Trends and innovations in industrial biocatalysis for the production of fine chemicals

2004; Elsevier BV; Volume: 15; Issue: 4 Linguagem: Inglês

10.1016/j.copbio.2004.06.011

1879-0429

Sven Panke, Martin Held, M. Wubbolts,

Chemical Synthesis and Analysis

Biocatalysis has become an established technology for the industrial manufacture of fine chemicals. In recent years, a multitude of chemical companies have embraced biocatalysis for the manufacture of desired stereoisomers, and new or improved methods for the synthesis of enantiomerically pure α- and β-amino acids, amines, amides, peptides, nitriles, alcohols, organic acids and epoxides have emerged. Furthermore, the selectivity and mild operational conditions of biocatalysts are increasingly applied in industry to modify complex target molecules. These recent innovations in the manufacture of industrial fine chemicals using biocatalysis are discussed from an industrial perspective.