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BIBTEX RIS

Clinical and laboratorial characterization and post-surgical follow-up of 87 patients with non-functioning pituitary macroadenomas

2013; Thieme Medical Publishers (Germany); Volume: 71; Issue: 5 Linguagem: Inglês

10.1590/0004-282x20130026

1678-4227

Paulo Andrade de Mello, Luciana Ansaneli Naves, Aldo Pereira Neto, Eduardo Henrique Oliveira, Ivan Coelho Ferreira, Antônio Santos de Araújo Júnior, Franz Jooji Onishi, Luíz Augusto Casulari,

Adrenal and Paraganglionic Tumors

It was to assess the main characteristics of patients undergoing pituitary tumor surgery.Eighty-seven patients (44 men; 44.8±13 years old) were included.The main symptoms were visual alterations (87.3%), headache (70.1%), diminished libido (34.4%), galactorrhea (22.9%) and hair loss (19.5%). The axes affected were gonadotropic (72.6%), thyrotropic (48.4%) and corticotropic (38.7%), without significant changes after surgery. The average largest tumor diameter was 3.1 cm before surgery and 1.56 cm after surgery. The most frequent postoperative complications were hydro-electrolyte and acid-base disorders (12%), diabetes insipidus (9%), visual field alterations (9%), liquoric fistula (8%) and nasal obstruction (7%). The patients were affected by more than one complication.Although a decrease in tumor volume was achieved through surgery, hormonal deficiencies persisted in most of the patients and new surgical approaches were necessary for dealing with tumor recurrence or persistence.