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Artigo Revisado por pares
BIBTEX RIS

The GABAA receptor α6 subunit gene (Gabra6) is tightly linked to the α1-γ2 subunit cluster on mouse chromosome 11

1997; Elsevier BV; Volume: 45; Issue: 1 Linguagem: Inglês

10.1016/s0169-328x(96)00290-2

ISSN

1872-6941

Autores

Kennon M. Garret, Dewan Haque, Douglas Berry, Iwona Niekrasz, Jiangping Gan, Andrej Rotter, Thomas W. Seale,

Tópico(s)

Neurogenesis and neuroplasticity mechanisms

Resumo

We have established that the GABAA receptor alpha 6 (Gabra6) and alpha 1 (Gabra 1) subunit genes are tightly linked on mouse chromosome 11 by analysing the strain distribution patterns of RFLPs for the two genes and microsatellite markers flanking these genes in 26 BXD recombinant inbred strains. These results further demonstrate clustering of the GABAA receptor subunit genes on mouse chromosomes and the synteny for these clusters between the mouse and human genomes.

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