Active Penetration of Fat into Adipose Tissue
1948; Nature Portfolio; Volume: 161; Issue: 4091 Linguagem: Inglês
10.1038/161482a0
ISSN1476-4687
AutoresB. Shapiro, Dinah Weissmann, V. Bentor, E. Wertheimer,
Tópico(s)Adipose Tissue and Metabolism
ResumoWHEN adipose tissue of the rat, depleted of part of its fat by prolonged hunger, is incubated with blood or serum of the same rat, a decrease in the fat content of the medium can be demonstrated. Killing the tissue by heating to 80° C. abolishes this effect. The addition to the medium of sodium fluoride (M/20 or M/40), or of sodium cyanide (M/500) also completely inhibits the disappearance of fatty acids. Sodium azide (M/ 1,000) had no inhibiting effect. The most marked decrease in the fat content of the medium was obtained with adipose tissue and blood of rats starved to 25 per cent loss of weight. With fat-laden adipose tissue of normal rats the effect was negligible or absent. No decrease in the fat content of the blood was found when the incubation was carried out at room temperature. The accompanying table summarizes these results.
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