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Long-Term Risk of Hypertension and Chronic Kidney Disease in Living Kidney Donors

2012; Elsevier BV; Volume: 44; Issue: 3 Linguagem: Inglês

10.1016/j.transproceed.2011.12.066

1873-2623

S.H. Kim, Hyeon Seok Hwang, Hye Eun Yoon, Y.K. Kim, Bum Soon Choi, In Sung Moon, J.C. Kim, Tae‐Kon Hwang, Y.S. Kim, Chul Woo Yang,

Organ Transplantation Techniques and Outcomes

The aim of this study was to assess the long-term risks of chronic kidney disease and arterial hypertension in living kidney donors. Donors who were followed for more than 1 year after nephrectomy were included. We assessed each donor's blood pressure, urine protein, and estimated glomerular filtration rate (eGFR). The follow-up rate was 11% (154 out of 1,356 donors), only 19% of whom were followed by nephrologists. Blood pressure had increased from 113/75 to 116/77 mm Hg (P < .01), urinary protein excretion after donation did not increase, and renal function was well preserved after donor nephrectomy. However, 33 patients (21.4%) showed a decreased eGFR of <60 mL/min/1.73 m2, and 3 donors developed end-stage renal disease that required renal replacement therapy. The follow-up rate of living donors after donation was low, and we observed an increased risk of developing chronic kidney disease after donation.