Chronic respiratory failure due to toxic epidermal necrosis in a 10 year old girl
2014; Taylor & Francis; Volume: 70; Issue: 1 Linguagem: Inglês
10.1179/2295333714y.0000000086
ISSN2295-3337
AutoresMatthieu Thimmesch, A Gilbert, David Tuerlinckx, E. Bodart,
Tópico(s)Polyomavirus and related diseases
ResumoToxic epidermal necrosis is a severe mucocutaneous disease with a high mortality rate. A third of the patients surviving the acute phase will develop pulmonary complications. The most frequent complication is bronchiolitis obliterans. Despite well-conducted treatment, in most cases, lung injury often leads to chronic respiratory failure. We describe here the case of a young patient that presented a toxic epidermal necrosis at the age of 3 years. Poor therapeutic compliance result in chronic respiratory failure and after 7 years of follow-up, pulmonary transplant remains the only long-term alternative. Close monitoring of respiratory symptoms in the course of toxic epidermal necrosis, intense treatment as soon as they appear and a long-term follow-up are essential to postpone chronic respiratory failure.
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