Challenges of Therapeutic Delivery Using Conducting Polymers
2012; Future Science Ltd; Volume: 3; Issue: 4 Linguagem: Inglês
10.4155/tde.12.19
ISSN2041-6008
AutoresLaura A. Poole‐Warren, Josef Goding, Rylie A. Green, Penny J. Martens,
Tópico(s)Advanced Sensor and Energy Harvesting Materials
ResumoTherapeutic DeliveryVol. 3, No. 4 CommentaryChallenges of therapeutic delivery using conducting polymersLaura Poole-Warren, Josef Goding, Rylie Green & Penny MartensLaura Poole-Warren* Author for correspondenceGraduate School of Biomedical Engineering, UNSW, Sydney, NSW 2052 Australia. , Josef GodingGraduate School of Biomedical Engineering, Rylie GreenGraduate School of Biomedical Engineering & Penny MartensGraduate School of Biomedical EngineeringPublished Online:29 Mar 2012https://doi.org/10.4155/tde.12.19AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleKeywords: conducting hydrogelsconducting polymerscontrolled releasedrug deliveryelectrical stimulationReferences1 Green RA, Lovell NH, Wallace GG, Poole-Warren LA. Conducting polymers for neural interfaces: challenges in developing an effective long-term implant. Biomaterials29(24–25),3393–3399 (2008).Crossref, Medline, CAS, Google Scholar2 Svirskis D, Travas-Sejdic J, Rodgers A, Garg S. Electrochemically controlled drug delivery based on intrinsically conducting polymers. J. Control. Release146(1),6–15 (2010).Crossref, Medline, CAS, Google Scholar3 Thompson BC, Moulton SE, Ding J et al. Optimising the incorporation and release of a neurotrophic factor using conducting polypyrrole. J. Control. Release116(3),285–294 (2006).Crossref, Medline, CAS, Google Scholar4 Green RA, Lovell NH, Poole-Warren LA. Impact of co-incorporating laminin peptide dopants and neurotrophic growth factors on conducting polymer properties. Acta Biomater.6(1),63–71 (2010).Crossref, Medline, CAS, Google Scholar5 Thompson BC, Richardson RT, Moulton SE et al. Conducting polymers, dual neurotrophins and pulsed electrical stimulation – dramatic effects on neurite outgrowth. J. Control. Release141(2),161–167 (2010).Crossref, Medline, CAS, Google Scholar6 Wadhwa R, Lagenaur CF, Cui XT. Electrochemically controlled release of dexamethasone from conducting polymer polypyrrole coated electrode. J. Control. Release110(3),531–541 (2006).Crossref, Medline, CAS, Google Scholar7 Mastragostino M, Soddu L. Electrochemical characterization of "n" doped polyheterocyclic conducting polymers – I. Polybithiophene. Electrochim. Acta35(2),463–466 (1990).Crossref, CAS, Google Scholar8 Kontturi K, Pentti P, Sundholm G. Polypyrrole as a model membrane for drug delivery. J. Electroanal. Chem.453(1–2),231–238 (1998).Crossref, CAS, Google Scholar9 Abidian MR, Kim DH, Martin DC. Conducting-polymer nanotubes for controlled drug release. Adv. Mater.18(4),405–409 (2006).Crossref, Medline, CAS, Google Scholar10 Geetha S, Rao CRK, Vijayan M, Trivedi DC. Biosensing and drug delivery by polypyrrole. Anal. Chim. Acta568(1–2),119–125 (2006).Crossref, Medline, CAS, Google Scholar11 Luo X, Cui XT. Sponge-like nanostructured conducting polymers for electrically controlled drug release. Electrochem. Commun.11(10),1956–1959 (2009).Crossref, Medline, CAS, Google Scholar12 Massoumi B, Entezami A. Electrochemically controlled binding and release of dexamethasone from conducting polymer bilayer films. J. Bioact. Compat. Polym.17(1),51–62 (2002).Crossref, CAS, Google Scholar13 Shain W, Spataro L, Dilgen J et al. Controlling cellular reactive responses around neural prosthetic devices using peripheral and local intervention strategies. IEEE Trans. Neural Syst. Rehabil. Eng.11(2),186–188 (2003).Crossref, Medline, Google Scholar14 Green RA, Lovell NH, Poole-Warren LA. Cell attachment functionality of bioactive conducting polymers for neural interfaces. Biomaterials30(22),3637–3644 (2009).Crossref, Medline, CAS, Google Scholar15 Schuettler M, Stiess S, King BV, Suaning GJ. Fabrication of implantable microelectrode arrays by laser cutting of silicone rubber and platinum foil. J. Neural Eng.2(1),S121 (2005).Crossref, Medline, CAS, Google Scholar16 Richardson RT, Wise AK, Thompson BC et al. Polypyrrole-coated electrodes for the delivery of charge and neurotrophins to cochlear neurons. Biomaterials30(13),2614–2624 (2009).Crossref, Medline, CAS, Google Scholar17 Collier JH, Camp JP, Hudson TW, Schmidt CE. Synthesis and characterization of polypyrrole–hyaluronic acid composite biomaterials for tissue engineering applications. J. Biomed. Mater. Res.50(4),574–584 (2000).Crossref, Medline, CAS, Google Scholar18 Massoumi B, Entezami A. Controlled release of sulfosalicylic acid during electrochemical switching of conducting polymer bilayers. Eur. Polym. J.37(5),1015–1020 (2001).Crossref, CAS, Google Scholar19 Kang G, Borgens RB, Cho Y. Well-ordered porous conductive polypyrrole as a new platform for neural interfaces. Langmuir27(10),6179–6184 (2011).Crossref, Medline, CAS, Google Scholar20 Luo X, Cui XT. Electrochemically controlled release based on nanoporous conducting polymers. Electrochem. Commun.11(2),402–404 (2009).Crossref, CAS, Google Scholar21 Green R, Williams C, Lovell N, Poole-Warren L. Novel neural interface for implant electrodes: improving electroactivity of polypyrrole through MWNT incorporation. J. Mater. Sci. Mater. Med.19(4),1625–1629 (2008).Crossref, Medline, CAS, Google Scholar22 Xiao Y, Ye X, He L, Che J. New carbon nanotube-conducting polymer composite electrodes for drug delivery applications. Polym. Intl61(2),190–196 (2012).Crossref, CAS, Google Scholar23 Luo X, Matranga C, Tan S, Alba N, Cui XT. Carbon nanotube nanoreservior for controlled release of anti-inflammatory dexamethasone. Biomaterials32(26),6316–6323 (2011).Crossref, Medline, CAS, Google Scholar24 George PM, Lavan DA, Burdick JA, Chen CY, Liang E, Langer R. Electrically controlled drug delivery from biotin-doped conductive polypyrrole. Adv. Mater.18(5),577–581 (2006).Crossref, CAS, Google Scholar25 Green RA, Baek S, Poole-Warren LA, Martens PJ. Conducting polymer-hydrogels for medical electrode applications. Sci. Technol. Adv. Mater.11(1),014107 (2010).Crossref, Medline, Google Scholar26 Lira LM, Barthus R, Torresi S. Conducting polymers and hydrogels for electrochemically controlled drug release devices. ECS Trans.3(29),105–114 (2007).Crossref, CAS, Google Scholar27 Lira LM, Córdoba DE, Torresi SI. Conducting polymer–hydrogel composites for electrochemical release devices: synthesis and characterization of semi-interpenetrating polyaniline–polyacrylamide networks. Electrochem. Commun.7(7),717–723 (2005).Crossref, CAS, Google Scholar28 Green RA, Hassarati RT, Goding JA et al. Conductive hydrogels. Mechanically robust hybrids for use as biomaterials. Macromol. Biosci. doi:10.1002/mabi.201100490 (Epub ahead of print) (2011).Google Scholar29 Small CJ, Too CO, Wallace GG. Responsive conducting polymer-hydrogel composites. Polym. Gels Netw.5(3),251–265 (1997).Crossref, CAS, Google Scholar30 Barthus RC, Lira LM, Córdoba DE Torresi SI. Conducting polymer–hydrogel blends for electrochemically controlled drug release devices. J. Braz. Chem. Soc.19(4),630–636 (2008).Crossref, CAS, Google ScholarFiguresReferencesRelatedDetailsCited ByCarbon-based nanogels as a synergistic platform for bioimaging and drug deliveryElectroactive material-based biosensors for detection and drug deliveryAdvanced Drug Delivery Reviews, Vol. 170PEDOT and PEDOT:PSS conducting polymeric hydrogels: A report on their emerging applicationsSynthetic Metals, Vol. 273Conducting polymer hydrogels for electrically responsive drug deliveryJournal of Controlled Release, Vol. 328Actively controlled local drug delivery using conductive polymer-based devicesApplied Physics Letters, Vol. 116, No. 1Electrochemically Controlled Drug Release from a Conducting Polymer Hydrogel (PDMAAp/PEDOT) for Local Therapy and Bioelectronics5 March 2019 | Advanced Healthcare Materials, Vol. 8, No. 10Organic Bioelectronic Tools for Biomedical Applications5 November 2015 | Electronics, Vol. 4, No. 4On demand delivery of ionic drugs from electro-responsive CNT hybrid films1 January 2015 | RSC Advances, Vol. 5, No. 56Is there a future for electrochemically assisted hemodialysis? Focus on the application of polypyrrole–nanocellulose compositesNanomedicine, Vol. 9, No. 7Improving Cochlear Implant Properties Through Conductive Hydrogel CoatingsIEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol. 22, No. 2 Vol. 3, No. 4 Follow us on social media for the latest updates Metrics Downloaded 225 times History Published online 29 March 2012 Published in print April 2012 Information© Future Science LtdKeywordsconducting hydrogelsconducting polymerscontrolled releasedrug deliveryelectrical stimulationFinancial & competing interests disclosureThe authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.No writing assistance was utilized in the production of this manuscript.PDF download
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