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Artigo Produção Nacional Revisado por pares
BIBTEX RIS

Perinatal or early-postnatal cytomegalovirus infection in preterm infants under 34 weeks gestation born to CMV-seropositive mothers within a high-seroprevalence population

2004; Elsevier BV; Volume: 145; Issue: 5 Linguagem: Inglês

10.1016/j.jpeds.2004.07.025

ISSN

1097-6833

Autores

Marisa Márcia Mussi‐Pinhata, Aparecida Yulie Yamamoto, Maria Aparecida do Carmo Rego, Patrícia Cristina Gomes Pinto, Márcia Soares Freitas da Motta, Cristina Calixto,

Tópico(s)

Infant Nutrition and Health

Resumo

In a prospective study, we evaluated the frequency, correlates, and clinical significance of perinatal or early-postnatal cytomegalovirus (CMV) infection in <34-week-gestation infants (n=95) born to CMV-seropositive mothers. None had congenital CMV infection. Overall, 21 (22.1%; 95% CI=14.2-31.8) infants were found to be infected; 10 excreted CMV at 30 days (OR=7.9, P <.01) was associated with infection. Only one (4.8%) of the infected infants was symptomatic. For <34-week-gestation infants, frequency of perinatal and early-postnatal CMV infection is high. Early or prolonged exposure to breast milk is an associated factor. However, most infections are asymptomatic, indicating that CMV infection in preterm infants within such a population is a serious problem infrequently.

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