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BIBTEX RIS

Paracoccidioidomycosis manifesting as oral lesions: clinical, cytological and serological investigation

1994; Wiley; Volume: 23; Issue: 2 Linguagem: Inglês

10.1111/j.1600-0714.1994.tb00262.x

1600-0714

Maria Regina Sposto, Maria José Soares Mendes‐Giannini, Rosângela Aparecida Moraes, Fernanda Cristina Branco, Crispian Scully,

Infectious Diseases and Mycology

Paracoccidioidomycosis (South American blastomycosis) is a systemic mycosis which can he associated with oral lesions. This study on a group of 14 patients showed oral lesions mainly on the gingival or alveolar mucosa with pulmonary involvement detectable on chest radiography in most. Microscopic detection of the fungus on a direct smear showed positive results in all 14 patients. Serological investigations including immunodiffusion, counterimmunoelectrophoresis and immunoblot were also positive in 100% of cases. The results suggest that direct smear together with serology may obviate the need for lesional biopsy for the diagnosis of oral Paracoccidioidomycosis.