Biotransformation of 6-gingerol and 6-shogaol by Aspergillus niger
1993; Elsevier BV; Volume: 34; Issue: 6 Linguagem: Inglês
10.1016/s0031-9422(00)90835-5
ISSN1873-3700
AutoresHironobu Takahashi, Toshihiro Hashimoto, Yoshiaki Noma, Yoshinori Asakawa,
Tópico(s)Ginseng Biological Effects and Applications
Resumo6-Gingerol and shogaol, the pungent constituents of Zingiber officinalis were biotransformed by Aspergillus niger. 6-Gingerol was converted to the corresponding primary alcohol as major product although a keto group is present in the molecule whereas the double bond and keto group of 6-shogaol were reduced and the terminal methyl group was further oxidized to afford a ketoalcohol and a diol. All metabolites obtained from both substrates are tasteless. The structures of the metabolises have been established by spectral evidence. The metabolic pathways of both substrates will be discussed.
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