Severe diaphragm weakness in multiple sclerosis.
1985; BMJ; Volume: 40; Issue: 8 Linguagem: Inglês
10.1136/thx.40.8.633
ISSN1468-3296
AutoresC. B. Cooper, Patrick Trend, C M Wiles,
Tópico(s)Peripheral Neuropathies and Disorders
ResumoRespiratory failure is only rarely associated with multiple sclerosis.' 2 We describe a patient in whom a diagnosis of demyelinating disease was established and who presented in relapse with acute bilateral diaphragm weakness associated with other signs suggestive of a lesion extending up to the cervicomedullary junction.He developed respiratory failure and required mechanical ventilation. Case reportA 41 year old caucasian male presented in February 1981 with vertigo, diplopia, paraesthesiae, and urinary reten- tion.He was ataxic and had an internuclear ophthalmo- plegia and bilateral extensor responses.Lumbar cerebro- spinal fluid showed 41 lymphocytes/mm3 and a protein con- centration of 2 g/l.He was treated with dexamethasone and recovered.In March 1982 he presented with typical left optic neuritis responding poorly to corticosteroid treatment.Later that year he had sensory disturbance over the trunk and gait ataxia.In May 1983
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