C-Reactive Protein Levels in Normal Tension Glaucoma
2005; Lippincott Williams & Wilkins; Volume: 14; Issue: 5 Linguagem: Inglês
10.1097/01.ijg.0000176932.06606.6e
ISSN1536-481X
AutoresIgal Leibovitch, Shimon Kurtz, Anat Kesler, Nataly Feithliher, Gabi Shemesh, Ben‐Ami Sela,
Tópico(s)Ocular Surface and Contact Lens
ResumoTo determine C-reactive protein (CRP) levels in patients with normal tension glaucoma (NTG).This study included 20 cases with NTG and 30 controls, with no history of ocular disease. Plasma CRP levels of all the study participants were determined using a highly sensitive CRP kit.Twenty cases (11 males, 9 females, mean age 69 +/- 5 years) with NTG and 30 age-matched controls (15 males, 15 females, mean age 68 +/- 6) were evaluated. Both groups had similar demographic parameters (age, sex, BMI). Plasma CRP levels were significantly higher in the NTG cases than in controls (median [range], 3.20 [0.17-8.4] mg/dL compared with 0.5 [0.1-3.2], P < 0.001). The mean plasma CRP level was significantly elevated in the NTG cases compared with the controls (3.21 +/- 0.6 mg/dL and 0.85 +/- 0.17 mg/dL, respectively, P < 0 0.01).Our findings suggest that higher CRP levels may be associated with NTG. It is possible that a vascular inflammatory process is involved in the etiology of this glaucoma.
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