Portal de Periódicos da CAPES

Artigo Acesso aberto Produção Nacional Revisado por pares

BIBTEX RIS

Does BCG revaccination protect against the development of asthma?

2012; Elsevier BV; Volume: 107; Issue: 2 Linguagem: Inglês

10.1016/j.rmed.2012.10.009

1532-3064

Cláudia Ribeiro de Andrade, Sérgio Souza da Cunha, Cristina Gonçalves Alvim, Maria Jussara Fernandes Fontes, Renata Marcos Bedran, Henrique A. Binato, Paulo Augusto Moreira Camargos,

Chronic Obstructive Pulmonary Disease (COPD) Research

Single BCG vaccination has been considered as a protective factor against asthma. However the effect of a second dose of BCG on the prevalence rate of asthma and asthma–allergic rhinitis–eczema comorbidity has not been studied exclusively among adolescents. In this ISAAC protocol-based cross sectional study we assessed the association between one single versus two doses of BCG among 2213 individuals aged 13–14 years old. We found no association between BCG revaccination and asthma, associated (OR = 0.68, 95% CI, 0.37–1.25) or not to allergic rhinitis and/or atopic eczema (OR = 1.07, 95% CI, 0.84–1.36).