An improved modification of ritter reaction
1989; Elsevier BV; Volume: 30; Issue: 5 Linguagem: Inglês
10.1016/s0040-4039(00)95260-2
ISSN1873-3581
AutoresA García Martínez, Roberto Martínez Álvarez, Enrique Teso Vilar, Amelia Garcı́a Fraile, M. Hanack, L. R. Subramanian,
Tópico(s)Chemical Synthesis and Analysis
ResumoThe reaction of alcohols 1 with trifluoromethane-sulfonic anhydride (Tf2O) in dichloromethane in presence of a 2:1 excess of nitriles 3 affords the corresponding amides 5 in good yields.
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