Antiviral activity of betulin, betulinic and betulonic acids against some enveloped and non-enveloped viruses

2003; Elsevier BV; Volume: 74; Issue: 5 Linguagem: Inglês

10.1016/s0367-326x(03)00123-0

ISSN

1873-6971

Autores

N. I. Pavlova, О. В. Савинова, С. Н. Николаева, E. I. Boreko, О. Б. Флехтер,

Tópico(s)

Phytochemistry and Biological Activities

Resumo

Antiviral properties of betulin, betulinic and betulonic acids were investigated in cell cultures infected with herpes simplex type I, influenza FPV/Rostock and ECHO 6 viruses. All studied triterpenes were active against herpes simplex virus. Betulin and especially betulinic acid also suppressed ECHO 6 virus reproduction.

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