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Choriocarcinoma arising from the pituitary fossa with extracranial metastasis: A review of the literature

1983; Elsevier BV; Volume: 19; Issue: 5 Linguagem: Inglês

10.1016/0090-3019(83)90149-0

1879-3339

Tatsuhito Yamagami, Hajime Handa, Juji Takeuchi, Kyo Niijima, Fukumi Furukawa,

Neuroblastoma Research and Treatments

Since Askanazy's first report on a case of primary intracranial choriocarcinoma in 1906, more than 60 cases have been reported so far. We add to that a case of intrasellar choriocarcinoma with suprasellar extension: A 12-year-old girl showed cranial nerve palsies, hypopituitarism, and abnormally high titers of human chorionic gonadotropin (HCG) in blood and in cerebrospinal fluid (CSF). She died 3 months after surgery. At autopsy, an intra- and suprasellar choriocarcinoma, which penetrated through the clivus into the cerebellopontine angle and metastasized remotely to the lungs, was confirmed. This rare case is presented with a thorough review of the literature.