C9 ORF 72 repeat expansion and bipolar disorder – is there a link? No mutation detected in a Sardinian cohort of patients with bipolar disorder
2014; Wiley; Volume: 16; Issue: 6 Linguagem: Inglês
10.1111/bdi.12210
ISSN1399-5618
AutoresGianluca Floris, Francesca Di Stefano, Claudia Pisanu, Caterina Chillotti, Maria Rita Murru, Donatella Congiu, Stefania Cuccu, Elisa Ruiu, Giuseppe Borghero, Antonino Cannas, Maria Giovanna Marrosu, Francesco Marrosu, Maria Del Zompo, Alessio Squassina,
Tópico(s)Amyotrophic Lateral Sclerosis Research
ResumoBipolar DisordersVolume 16, Issue 6 p. 667-668 Letter to the Editor C9ORF72 repeat expansion and bipolar disorder – is there a link? No mutation detected in a Sardinian cohort of patients with bipolar disorder Gianluca Floris, Corresponding Author Gianluca Floris Department of Neurology, Teaching Hospital of Cagliari and University of Cagliari Corresponding author: Gianluca Floris, MD Department of Neurology University of Cagliari Sst 554 09042 Monserrato Italy Fax: +3907051096497 E-mail: [email protected]Search for more papers by this authorFrancesca Di Stefano, Francesca Di Stefano Department of Neurology, Teaching Hospital of Cagliari and University of CagliariSearch for more papers by this authorClaudia Pisanu, Claudia Pisanu Laboratory of Pharmacogenomics, Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of CagliariSearch for more papers by this authorCaterina Chillotti, Caterina Chillotti Unit of Clinical Pharmacology, Teaching HospitalSearch for more papers by this authorMaria Rita Murru, Maria Rita Murru Multiple Sclerosis Center Laboratory, University of Cagliari, Cagliari, ItalySearch for more papers by this authorDonatella Congiu, Donatella Congiu Laboratory of Pharmacogenomics, Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of CagliariSearch for more papers by this authorStefania Cuccu, Stefania Cuccu Multiple Sclerosis Center Laboratory, University of Cagliari, Cagliari, ItalySearch for more papers by this authorElisa Ruiu, Elisa Ruiu Department of Neurology, Teaching Hospital of Cagliari and University of CagliariSearch for more papers by this authorGiuseppe Borghero, Giuseppe Borghero Department of Neurology, Teaching Hospital of Cagliari and University of CagliariSearch for more papers by this authorAntonino Cannas, Antonino Cannas Department of Neurology, Teaching Hospital of Cagliari and University of CagliariSearch for more papers by this authorMaria Giovanna Marrosu, Maria Giovanna Marrosu Multiple Sclerosis Center Laboratory, University of Cagliari, Cagliari, ItalySearch for more papers by this authorFrancesco Marrosu, Francesco Marrosu Department of Neurology, Teaching Hospital of Cagliari and University of CagliariSearch for more papers by this authorMaria Del Zompo, Maria Del Zompo Laboratory of Pharmacogenomics, Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari Unit of Clinical Pharmacology, Teaching HospitalSearch for more papers by this authorAlessio Squassina, Alessio Squassina Laboratory of Pharmacogenomics, Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of CagliariSearch for more papers by this author Gianluca Floris, Corresponding Author Gianluca Floris Department of Neurology, Teaching Hospital of Cagliari and University of Cagliari Corresponding author: Gianluca Floris, MD Department of Neurology University of Cagliari Sst 554 09042 Monserrato Italy Fax: +3907051096497 E-mail: [email protected]Search for more papers by this authorFrancesca Di Stefano, Francesca Di Stefano Department of Neurology, Teaching Hospital of Cagliari and University of CagliariSearch for more papers by this authorClaudia Pisanu, Claudia Pisanu Laboratory of Pharmacogenomics, Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of CagliariSearch for more papers by this authorCaterina Chillotti, Caterina Chillotti Unit of Clinical Pharmacology, Teaching HospitalSearch for more papers by this authorMaria Rita Murru, Maria Rita Murru Multiple Sclerosis Center Laboratory, University of Cagliari, Cagliari, ItalySearch for more papers by this authorDonatella Congiu, Donatella Congiu Laboratory of Pharmacogenomics, Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of CagliariSearch for more papers by this authorStefania Cuccu, Stefania Cuccu Multiple Sclerosis Center Laboratory, University of Cagliari, Cagliari, ItalySearch for more papers by this authorElisa Ruiu, Elisa Ruiu Department of Neurology, Teaching Hospital of Cagliari and University of CagliariSearch for more papers by this authorGiuseppe Borghero, Giuseppe Borghero Department of Neurology, Teaching Hospital of Cagliari and University of CagliariSearch for more papers by this authorAntonino Cannas, Antonino Cannas Department of Neurology, Teaching Hospital of Cagliari and University of CagliariSearch for more papers by this authorMaria Giovanna Marrosu, Maria Giovanna Marrosu Multiple Sclerosis Center Laboratory, University of Cagliari, Cagliari, ItalySearch for more papers by this authorFrancesco Marrosu, Francesco Marrosu Department of Neurology, Teaching Hospital of Cagliari and University of CagliariSearch for more papers by this authorMaria Del Zompo, Maria Del Zompo Laboratory of Pharmacogenomics, Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari Unit of Clinical Pharmacology, Teaching HospitalSearch for more papers by this authorAlessio Squassina, Alessio Squassina Laboratory of Pharmacogenomics, Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of CagliariSearch for more papers by this author First published: 05 May 2014 https://doi.org/10.1111/bdi.12210Citations: 9Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References 1Floris G, Borghero G, Cannas A et al. Bipolar affective disorder preceding frontotemporal dementia in a patient with C9ORF72 mutation: is there a genetic link between these two disorders? J Neurol 2013; 260: 1155–1157. 10.1007/s00415-013-6833-2 PubMedWeb of Science®Google Scholar 2 American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th edn. Washington, DC: American Psychiatric Association, 1994. PubMedGoogle Scholar 3Meisler MH, Grant AE, Jones JM et al. C9ORF72 expansion in a family with bipolar disorder. Bipolar Disord 2013; 15: 326–332. 10.1111/bdi.12063 CASPubMedWeb of Science®Google Scholar 4Galimberti D, Reif A, Dell'Osso B et al. C9ORF72 hexanucleotide repeat expansion as a rare cause of bipolar disorder. Bipolar Disord 2013. doi: 10.1111/bdi.12169. [Epub ahead of print]. 10.1111/bdi.12169 PubMedWeb of Science®Google Scholar 5Chiò A, Borghero G, Restagno G et al. Clinical characteristics of patients with familial amyotrophic lateral sclerosis carrying the pathogenic GGGGCC hexanucleotide repeat expansion of C9ORF72. Brain 2012; 135: 784–793. 10.1093/brain/awr366 PubMedWeb of Science®Google Scholar 6Piazza A, Mayr WR, Contu L et al. Genetic and population structure of four Sardinian villages. Ann Hum Genet 1985; 49: 47–63. 10.1111/j.1469-1809.1985.tb01675.x CASPubMedWeb of Science®Google Scholar 7Endicott J, Spitzer R. A diagnostic interview: the schedule for affective disorders and schizophrenia. Arch Gen Psychiatry 1978; 35: 837–844. 10.1001/archpsyc.1978.01770310043002 CASPubMedWeb of Science®Google Scholar 8Majounie E, Renton AE, Mok K et al. Frequency of the C9ORF72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study. Lancet Neurol 2012; 11: 323–330. 10.1016/S1474-4422(12)70043-1 CASPubMedWeb of Science®Google Scholar 9Van der Zee J, Gijselinck I, Dillen L et al. A Pan-European study of the C9ORF72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats. Hum Mutat 2013; 34: 363–373. 10.1002/humu.22244 CASPubMedWeb of Science®Google Scholar Citing Literature Volume16, Issue6September 2014Pages 667-668 ReferencesRelatedInformation
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