ADENOSINE DEAMINASE ACTIVITY IN LYMPHOCYTES
1977; Wiley; Volume: 37; Issue: 1 Linguagem: Inglês
10.1111/j.1365-2141.1977.tb08825.x
ISSN1365-2141
AutoresJ. L. Sullivan, William Osborne, Ralph Wedgwood,
Tópico(s)Autoimmune and Inflammatory Disorders Research
ResumoThe presence of high levels of alkaline phosphatase in the circulating neutrophils of some patients with hairy cell leukaemia (HCL) has been mentioned in the course of more extensive reports or reviews on the disease (Katayama & Finkel, 1974; Rosenszajn et al, 1976) but does not seem to have yet become clearly recognized as a characteristic feature.We have previously reported that all of five typical cases of HCL had leucocyte alkaline phosphatase (LAP) scores ranging between 160 and 280 (NR IS-IOO), whereas three somewhat atypical cases had lower scores, ranging from 50 to 1 3 0 (Burns et al, 1976).We have since had the opportunity to carry out repeated LAP scoring on 10 further typical cases of HCL.All gave consistently high scores,
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