Effect of Chemotherapy and/or Head Irradiation on Survival of Mice with Intracranial Glioma
1971; Radiological Society of North America; Volume: 101; Issue: 1 Linguagem: Inglês
10.1148/101.1.187
ISSN1527-1315
AutoresJ M Thomson, Yosh Maruyama, Samuel Schwartz, Eric Hahn,
Tópico(s)Brain Metastases and Treatment
ResumoMice bearing intracranial gliomas were treated with BCNU (1,3-bis(chloroethyl)-l-nitrosourea), Ara-C (cytosine arabinoside), and copper hematoporphyrin with and without head irradiation. The strongest effect was noted with BCNU, as would be expected from brain-barrier and cell age-specific activity of the drug.
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