Ectopic glomerular structures in the olfactory bulb of neonatal and adult mice
1980; Elsevier BV; Volume: 187; Issue: 2 Linguagem: Inglês
10.1016/0006-8993(80)90217-6
ISSN1872-6240
AutoresP. P. C. Graziadei, David W. Samanen,
Tópico(s)Advanced Chemical Sensor Technologies
ResumoThe olfactory system has to process the limitless chemical world of odors. Everything begins in the nose in which, the volatile odorant molecules enter in rhythm with our breathing. On the forefront are the olfactory sensory neurons (OSNs), which process sensory information by integrating simultaneously, as soon as the first sniff, quantitative, qualitative, and temporal features of stimuli and, send to the next level, the olfactory bulb (OB) a well-defined description of stimulus attributes. At the OB level, the incoming peripheral message is sorted and in so doing designs an incident functional map. At this level, the sensory information is furthermore amplified, filtered, and transformed, this probably resulting in an olfactory code based on fine temporal tuning of spike activities within mitral-tufted neuron assemblies. Such a multiplexed code based on both temporal and frequency parameters would further use gamma oscillations as a global clock and appears as especially adapted to face multidimensional stimuli the inputs of which are fragmented across OB. Then the processed olfactory information diverges to the piriform cortex where the olfactory percept forms. At the next stage, the olfactory information is combined together with the information from other sensory organs and compared with previous experiences to give the final odor perception. As all the other senses, olfaction can display genetic, gender, and aging variations in performances. In addition, the olfactory function can be impacted by stress, circadian rhythm, and in women by the reproductive neuroendocrine status.
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