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Antihypertensive action of a procyanidin glycoside from Rhamnus lycioides

1991; Elsevier BV; Volume: 31; Issue: 1 Linguagem: Inglês

10.1016/0378-8741(91)90149-8

1872-7573

María Carmen Terencio, María‐Jesús Sanz, M. Payá,

Phytochemicals and Antioxidant Activities

The antihypertensive action of a procyanidin glycoside isolated from Rhamnus lycioides aerial parts was studied in spontaneously and renal hypertensive rats. This compound, like 20 micrograms/kg i.v. of captopril, produced a very clear in vivo inhibition of angiotensin I converting enzyme when given at a dose of 3 mg/kg i.v.