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Reasons for calibration standard curve slope variation in LC–MS assays and how to address it

2014; Future Science Ltd; Volume: 6; Issue: 11 Linguagem: Inglês

10.4155/bio.14.71

1757-6199

Yue Zhao, Guowen Liu, Jim X Shen, Anne‐Françoise Aubry,

Bacterial Identification and Susceptibility Testing

BioanalysisVol. 6, No. 11 CommentaryReasons for calibration standard curve slope variation in LC–MS assays and how to address itYue Zhao, Guowen Liu,, Jim X Shen & Anne-Francoise AubryYue ZhaoBioanalytical Sciences Department, Research & Development, Bristol–Myers Squibb Co, Route 206 & Province Line Road, Princeton, NJ 08543, USA, Guowen LiuBioanalytical Sciences Department, Research & Development, Bristol–Myers Squibb Co, Route 206 & Province Line Road, Princeton, NJ 08543, USA,, Jim X ShenBioanalytical Sciences Department, Research & Development, Bristol–Myers Squibb Co, Route 206 & Province Line Road, Princeton, NJ 08543, USA & Anne-Francoise AubryBioanalytical Sciences Department, Research & Development, Bristol–Myers Squibb Co, Route 206 & Province Line Road, Princeton, NJ 08543, USAPublished Online:21 Jul 2014https://doi.org/10.4155/bio.14.71AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInRedditEmail View articleKeywords: calibration standard curveLC–MS/MSregulated bioanalysisslope variationReferences1 Garofolo F, Rocci ML Jr, Dumont I et al. 2011 White Paper on recent issues in bioanalysis and regulatory findings from audits and inspections. 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The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.No writing assistance was utilized in the production of this manuscript.PDF download