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Myoclonus in Alzheimer Disease

1976; American Medical Association; Volume: 33; Issue: 4 Linguagem: Inglês

10.1001/archneur.1976.00500040062010

1538-3687

Alan I. Faden,

Lysosomal Storage Disorders Research

Myoclonus in association with dementia of later adult life has been considered almost pathognomonic of Creutzfeldt-Jakob disease. However, myoclonus may also be seen with Alzheimer disease, and when the myoclonus occurs as an early manifestation of Alzheimer disease, distinction from Creutzfeldt-Jakob disease may prove difficult.