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Artigo Produção Nacional Revisado por pares
BIBTEX RIS

Synthesis of amphiphilic galactopyranosyl diamines and amino alcohols as antitubercular agents

2007; Elsevier BV; Volume: 42; Issue: 8 Linguagem: Inglês

10.1016/j.ejmech.2007.01.009

ISSN

1768-3254

Autores

Mauro V. de Almeida, Mireille Le Hyaric, Giovanni W. Amarante, Maria Cristina S. Lourenço, Marcelo Luiz Lima Brandão,

Tópico(s)

Biopolymer Synthesis and Applications

Resumo

Mono- and diacylated derivatives of galactopyranosyl amines were obtained from d-galactose, via aminated intermediates prepared by reaction of 6-deoxy-6-iodo-1,2:3,4-di-O-isopropylidene-α-d-galactopyranose with 1,3-propanediamine, 1,2-ethanediamine or ethanolamine. Monoacylated derivatives displayed antitubercular activity.

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