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The Significance of Candida albicans in Human Sputum

1960; Massachusetts Medical Society; Volume: 263; Issue: 2 Linguagem: Inglês

10.1056/nejm196007142630204

1533-4406

Gerald L. Baum,

Chronic Obstructive Pulmonary Disease (COPD) Research

THE presence of fungi (both yeasts and molds) in sputum has been of increasing interest since the advent of antibiotics and steroids as common therapeutic agents. In addition, the development of two potent antifungal antibiotics, nystatin and amphotericin B, has made urgent the question of significance of positive sputum cultures for fungi.In general the extensive use of steroids, penicillin, streptomycin and the tetracycline drugs has led to the more frequent finding of fungi in sputum cultures. However, the importance of this finding in relation to pulmonary disease is not understood since the organisms represent, for the most part, normal . . .