Ovarian ornithine decarboxylase induction: A specific and rapid in vivo bioassay of LH

1977; Academic Press; Volume: 17; Issue: 1 Linguagem: Inglês

10.1016/0006-2944(77)90010-2

ISSN

1557-7996

Autores

Aida Nureddin,

Tópico(s)

Metabolism and Genetic Disorders

Resumo

Ovarian ornithine decarboxylase was found to be specifically induced by LH in the 22- to 32-day-old rats. Maximal induction occurred with the 32-day-old rat but was found to be a function of the concentration of LH at all ages. Based on these findings, an in vivo bioassay of LH was developed. Its effective dose range is from 15 to 40 μg LH/kg. The application of this bioassay to the estimation of LH in different samples was discussed.

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