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The impact of improved glycaemic control with GLP-1 receptor agonist therapy on diabetic retinopathy

2014; Elsevier BV; Volume: 103; Issue: 3 Linguagem: Inglês

10.1016/j.diabres.2013.12.041

1872-8227

Lakshminarayanan Varadhan, Tracy Humphreys, Adrian B Walker, George Varughese,

Neurological and metabolic disorders

Rapid improvement in glycaemic control with GLP-1 receptor agonist (RA) therapy has been reported to be associated with significant progression of diabetic retinopathy. This deterioration is transient, and continuing GLP-1 RA treatment is associated with reversal of this phenomenon. Pre-existent maculopathy, higher grade of retinopathy and longer duration of diabetes may be risk factors for persistent deterioration.