Chemistry of neocarzinostatin-mediated degradation of d(GCATGC). Mechanism of spontaneous thymine release
1989; Elsevier BV; Volume: 30; Issue: 32 Linguagem: Inglês
10.1016/s0040-4039(01)80706-1
ISSN1873-3581
AutoresHiroshi Kawabata, Hiroshi Takeshita, Tsuyoshi Fujiwara, Hiroshi Sugiyama, Teruo Matsuura, Isao Saito,
Tópico(s)Advanced Fluorescence Microscopy Techniques
ResumoIdentification and quantification of the oxidized deoxyribose moiety associated with spontaneous thymine release in neocarzinostatin-mediated degradation of self-complementary hexanucleotide d(GCATGC) have been described. Criegee-type rearrangement of C-5′ hydroperoxide intermediate has been proposed.
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