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Trauma and tranexamic acid

2013; Wiley; Volume: 199; Issue: 5 Linguagem: Inglês

10.5694/mja13.10747

1326-5377

Russell L. Gruen, Ian Jacobs, Michael C. Reade,

Trauma, Hemostasis, Coagulopathy, Resuscitation

Medical Journal of AustraliaVolume 199, Issue 5 p. 310-311 Editorial Trauma and tranexamic acid Russell L Gruen MB BS, PhD, FRACS, Corresponding Author Russell L Gruen MB BS, PhD, FRACS Professor of Surgery and Public Health; Director [email protected] The Alfred and Monash University, Melbourne, VIC. National Trauma Research Institute, Melbourne, VIC.Correspondence: [email protected]Search for more papers by this authorIan G Jacobs BAppSc, PhD, RN, Ian G Jacobs BAppSc, PhD, RN Professor of Resuscitation and Pre-hospital Care; Clinical Services Director Emergency Medicine, University of Western Australia, Perth, WA. St John Ambulance (Western Australia), Perth, WA.Search for more papers by this authorMichael C Reade DPhil, FANZCA, FCICM, Michael C Reade DPhil, FANZCA, FCICM Defence Professor of Military Medicine and Surgery, and Intensivist; Lieutenant Colonel Burns, Trauma and Critical Care Research Centre, University of Queensland, Brisbane, QLD. Joint Health Command, Australian Defence Force, Canberra, ACT.Search for more papers by this author Russell L Gruen MB BS, PhD, FRACS, Corresponding Author Russell L Gruen MB BS, PhD, FRACS Professor of Surgery and Public Health; Director [email protected] The Alfred and Monash University, Melbourne, VIC. National Trauma Research Institute, Melbourne, VIC.Correspondence: [email protected]Search for more papers by this authorIan G Jacobs BAppSc, PhD, RN, Ian G Jacobs BAppSc, PhD, RN Professor of Resuscitation and Pre-hospital Care; Clinical Services Director Emergency Medicine, University of Western Australia, Perth, WA. St John Ambulance (Western Australia), Perth, WA.Search for more papers by this authorMichael C Reade DPhil, FANZCA, FCICM, Michael C Reade DPhil, FANZCA, FCICM Defence Professor of Military Medicine and Surgery, and Intensivist; Lieutenant Colonel Burns, Trauma and Critical Care Research Centre, University of Queensland, Brisbane, QLD. Joint Health Command, Australian Defence Force, Canberra, ACT.Search for more papers by this author First published: 02 September 2013 https://doi.org/10.5694/mja13.10747Citations: 40Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References 1Shakur H, Roberts I, Bautista R, et al. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010; 376: 23–32. 2Pusateri AE, Weiskopf RB, Bebarta V, et al. Tranexamic acid and trauma: current status and knowledge gaps with recommended research priorities. Shock 2013; 39: 121–126. 3Napolitano LM, Cohen MJ, Cotton BA, et al. Tranexamic acid in trauma: how should we use it? J Trauma Acute Care Surg 2013; 74: 1575–1586. 4Ker K, Edwards P, Perel P, et al. Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis. BMJ 2012; 344: e3054. 5Roberts I, Shakur H, Afolabi A, et al. The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. Lancet 2011; 377: 1096–1101.e1-2. 6Shakur H, Roberts I, Piot P, et al. A promise to save 100 000 trauma patients. Lancet 2012; 380: 2062–2063. 7Gruen RL, Mitra B. Tranexamic acid for trauma. Lancet 2011; 377: 1052–1054. 8Morrison JJ, Dubose JJ, Rasmussen TE, Midwinter MJ. Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study. Arch Surg 2012; 147: 113–119. 9Mitra B, Cameron PA, Gruen RL. Aggressive fresh frozen plasma (FFP) with massive blood transfusion in the absence of acute traumatic coagulopathy. Injury 2012; 43: 33–37. 10Ioannidis JP. Contradicted and initially stronger effects in highly cited clinical research. JAMA 2005; 294: 218–228. 11Goldberger JJ, Buxton AE. Personalized medicine vs guideline-based medicine. JAMA 2013; 309: 2559–2560. Citing Literature Volume199, Issue5Obstetrics and gynaecology issueSeptember 2013Pages 310-311 ReferencesRelatedInformation