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Normal and hydronephrotic kidney: evaluation of renal function with contrast-enhanced MR imaging.

1987; Radiological Society of North America; Volume: 165; Issue: 3 Linguagem: Inglês

10.1148/radiology.165.3.3685363

1527-1315

R. Kikinis, Gustav K. von Schulthess, P.A. de Jager, Richard Dürr, M. Bino, Walter Kuoni, O. Kübler,

Fetal and Pediatric Neurological Disorders

Four healthy volunteers and six patients with hydronephrosis underwent magnetic resonance (MR) imaging after the injection of gadolinium-diethylenetriaminepenta-aceticacid for the assessment of renal function. Coronal angulated 10-second images were obtained during suspended respiration (inspiratory apnea) and showed excellent anatomic detail. In healthy volunteers, the renal cortex showed an increase in signal intensity after Gd-DTPA injection, and the renal medulla showed a precipitous decrease in intensity approximately 1 minute after injection, followed by a gradual increase in intensity. The renal pelvis showed a gradual decrease in intensity after several minutes, with occasional signal-void areas in adjacent structures. In patients with hydronephrosis, the decrease in intensity in the medulla and pelvis was not observed; instead, an increase in intensity occurred. The physiologic function of glomerular filtration and in vitro results of serial dilutions of Gd-DTPA suggest that the decrease in intensity is due to T2 and susceptibility effects occurring at high concentrations of Gd-DTPA.