Protective Effect of Cysteamine at Fractionated Irradiation: I. Lethality up to 30 days after last irradiation
1963; Taylor & Francis; Volume: 1; Issue: 6 Linguagem: Inglês
10.3109/02841866309134123
ISSN0567-8064
AutoresArne Nelson, Ola Hertzberg, Inga‐Britt Henricsson,
Tópico(s)Chemical synthesis and pharmacological studies
ResumoGroups of mice were exposed to fraction doses at various time intervals in order to investigate the protective effect of cysteamine at sublethal levels of irradiation. Half the number of animals were given cysteamine before each irradiation. A simple mathematical model, which fitted the results regarding the short term lethal effects, was used. Cysteamine appears to act by producing a dose reduction effect and not an enhancement of the recovery. (auth)
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