Artigo Revisado por pares

Familial mesothelioma: A report of two families

1989; Elsevier BV; Volume: 20; Issue: 2 Linguagem: Inglês

10.1016/0046-8177(89)90173-1

ISSN

1532-8392

Autores

Samuel P. Hammar, Dawn Bockus, Franque Remington, Susan Freidman, Gordon D. LaZerte,

Tópico(s)

Pleural and Pulmonary Diseases

Resumo

Five reports of familial mesothelioma in which mesotheliomas occurred in two or more family members have been recorded in the medical literature. In this report, we describe two examples of familial mesothelioma. In one family, three brothers who worked in the asbestos insulation industry developed mesothelioma. In the second family, the father, who was occupationally exposed to asbestos, died from a tubulopapillary peritoneal mesothelioma 11 years before his son died from an identical histologic type of peritoneal mesothelioma. Our report, as with those previously recorded, suggests that genetic factors may be important in the genesis of some mesotheliomas.

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