Artigo Acesso aberto Produção Nacional Revisado por pares

Anticorpos catalíticos: expandindo o alcance da catálise enzimática

1998; Brazilian Chemical Society; Volume: 21; Issue: 1 Linguagem: Inglês

10.1590/s0100-40421998000100014

ISSN

1678-7064

Autores

Giselle Z. Justo,

Tópico(s)

Click Chemistry and Applications

Resumo

THE SCOPE OF ENZYMATIC CATALYSIS.The vast binding repertoire of the immune system has been exploited for the generation of tailor-made selective catalysts.Since the first reports of chemical reactions catalyzed by antibodies were published, research in this field, which borders chemistry and biology, has been rapidly established and a number of catalytic antibodies that carry out a wide range of reactions, have been developed.Recent advances have led to antibodies that catalyse complex, multi-step reactions and difficult chemical transformations, as well as reactions that do not have an organic equivalent at all.Current research in this field has been devoted to practical applications of this technology.

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