A convenient synthesis of L ‐1‐methylhistidine and L ‐1‐ethylhistidine
1972; Royal Netherlands Chemical Society; Volume: 91; Issue: 3 Linguagem: Inglês
10.1002/recl.19720910302
ISSN1878-7096
AutoresH. C. Beyerman, L. Maat, A. van Zon,
Tópico(s)Carbohydrate Chemistry and Synthesis
ResumoAbstract Alkylation of the easily accessible methyl ester of L ‐ N a ,3‐dibenzoylhistidine with the aid of trimethyl‐ and triethyloxonium fluoroborate followed by decomposition with water and acid hydrolysis yielded L ‐1 ‐methyl‐ and L ‐1‐ethylhistidine respectively. Comparison with natural L ‐1‐methylhistidine confirmed the structure and optical purity.
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