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Absolute quantification of intracellular Na+ using triple-quantum-filtered sodium-23 NMR

1991; Elsevier BV; Volume: 93; Issue: 1 Linguagem: Inglês

10.1016/0022-2364(91)90032-o

1557-8968

Jonathan L. Allis, Anne‐Marie L. Seymour, George K. Radda,

Advanced MRI Techniques and Applications

We have developed a method for the absolute quantification of triple-quantum-filtered spectra of spin-3/2 nuclei. The method is illustrated by measuring the amount of intracellular Na+ in the perfused rat heart. There is good agreement between the result determined by the triple-quantum method and that measured using a simple single-quantum pulse-and-collect experiment.