Artigo Acesso aberto Revisado por pares

Anti-Nociceptive And Anti-Inflammatory Activities Of Aqueous Leaves Extract Of <i>Ocimum gratissimum ( Labiate )</i> In Rodents

2008; African Traditional Herbal Medicine Supporters Initiative (ATHMSI); Volume: 5; Issue: 2 Linguagem: Inglês

10.4314/ajtcam.v5i2.31265

ISSN

2505-0044

Autores

Y Tanko, G. M. Magaji, M Yerima, Rabiu Abdussalam Magaji, Aminu Mohammed,

Tópico(s)

Medicinal Plants and Neuroprotection

Resumo

The aqueous leaves extract of Ocimum gratissimum was investigated for anti-nociceptive and antiinflammatory effects in mice and rats. The models used to study the effect on nociception are the acetic acidinduced abdominal constriction test, hot- plate method in mice. The anti-inflammatory effect was investigated employing the formalin-induced hind–paw oedema in rats. The extract caused a significant (p

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