Design and syntheses of 4-acylaminopyridine derivatives: Novel high affinity choline uptake enhancers II
1995; Elsevier BV; Volume: 5; Issue: 14 Linguagem: Inglês
10.1016/0960-894x(95)00242-l
ISSN1464-3405
AutoresH. CHAKI, Haruko Yamabe, Mamoru Sugano, Shuji Morita, Tomoko Bessho, Reiko Tabata, Kenichi Saito, Mitsuo Egawa, Akihiro Tobe, Yasuhiro Morinaka,
Tópico(s)Calcium signaling and nucleotide metabolism
ResumoAbstract 4-Acylaminopyridine derivatives were synthesized and found to have high affinity choline uptake improvement activity. Optimum activity was obtained when the n-propylcarbonyl group was introduced as the acyl moiety. A series of 2-oxo-1-pyrrolidineacetyl substituted derivatives also showed activity.
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