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Aerosolized Pentamidine and Disseminated infection with Pneumocystis carinii

1989; American College of Physicians; Volume: 111; Issue: 5 Linguagem: Inglês

10.7326/0003-4819-111-5-442

1539-3704

Terrence G. Sparling, Sunny R. Dong, Csaba Hegedűs, David R. Burdge,

Tuberculosis Research and Epidemiology

Letters and Corrections1 September 1989Aerosolized Pentamidine and Disseminated infection with Pneumocystis cariniiTerrence G. Sparling, MD, Sunny R. Dong, MApSc, MD, Csaba Hegedus, MD, David R. Burdge, MDTerrence G. Sparling, MDSearch for more papers by this author, Sunny R. Dong, MApSc, MDSearch for more papers by this author, Csaba Hegedus, MDSearch for more papers by this author, David R. Burdge, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-111-5-442 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: Pulmonary infection with Pneumocystis carinii occurs commonly in patients with the acquired immunodeficiency syndrome (AIDS), but extrapulmonary and disseminated infection remains rare. Previously reported disseminated infection has almost invariably occurred in patients with overwhelming pneumonitis (1). We report a case of disseminated P. carinii infection in a patient with AIDS who received aerosolized pentamidine prophylaxis and who had no evidence of pulmonary disease.A 27-year-old homosexual man with AIDS presented in October 1988 with fever, weight loss; progressive mediastinal, hilar, and cervical lymphadenopathy; and a rapidly enlarging liver. From January to September 1988 he had...References1. UngerRosenblumKrown PMS. Disseminated Pneumocystis carinii infection in a patient with acquired immune deficiency syndrome. Hum Pathol. 1988;19:113-6. CrossrefMedlineGoogle Scholar2. BlumenfeldBasgozOwenSchmidt WNWD. Granulomatous pulmonary lesions in patients with acquired immunodeficiency syndrome (AIDS) and Pneumocystis carinii infection. Ann Intern Med. 1988;109:505-7. LinkGoogle Scholar3. DynerLangBuschGordon TWDP. Intravascular and pleural involvement by Pneumocystis carinii in a patient with the acquired immunodeficiency syndrome (AIDS). Ann Intern Med. 1989;111:94-5. LinkGoogle Scholar4. ConteGolden JJ. Concentrations of aerosolized pentamidine in bronchoalveolar lavage, systemic absorption, and excretion. Antimicrob Agents Chemother. 1988;32:1490-3. CrossrefMedlineGoogle Scholar1. PobleteRodriguezFoustReddySaldana RKRKM. Pneumocystis carinii hepatitis in the acquired immunodeficiency syndrome (AIDS). Ann Intern Med. 1989;110:737-8. LinkGoogle Scholar2. HardyNorthfeltDrake WDT. Fatal, disseminated pneumocystosis in a patient with AIDS receiving prophylactic aerosolized pentamidine. Am JMed. 1989[In press]. Google Scholar3. PiotGatheDel JuncoStoolTrujillo DJGEJ. Splenic pneumocystosis. Poster M.B.P.377. In: Abstracts, V International Conference on AIDS. Montreal, Quebec, Canada; 1989:284. Google Scholar4. Ward D. Disseminated granulomatous pneumocystosis in a patient receiving aerosolized pentamidine prophylaxis. Poster M.B.P.378. In: Abstracts, V International Conference on AIDS. Montreal, Quebec, Canada; 1989:284. Google Scholar5. MontgomeryDebsLuce ARJ. Selective delivery of pentamidine to the lungs by aerosol. Am Rev Resp Dis. 1988;137:477-8. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Terrence G. Sparling, MD; Sunny R. Dong, MApSc, MD; Csaba Hegedus, MD; David R. 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Soo Hoo, MD, MPH, Zab Mohsenifar, MD, Richard D. Meyer, MDLes pneumocystoses extra-pulmonairesEXTRAPULMONARY PNEUMOCYSTOSIS IN PATIENTS TAKING AEROSOLISED PENTAMIDINE 1 September 1989Volume 111, Issue 5Page: 442-443KeywordsAIDSFeversHomosexualsInfectious diseasesLiverPneumocystisPneumonitisProphylaxisPulmonary diseasesWeight loss ePublished: 1 December 2008 Issue Published: 1 September 1989 PDF downloadLoading ...