Portal de Periódicos da CAPES

Artigo Produção Nacional Revisado por pares

BIBTEX RIS

Biochemical studies on copper, copper oxidase, magnesium, sulfur, calcium and phosphorus in cancer of the breast

1965; Elsevier BV; Volume: 12; Issue: 4 Linguagem: Inglês

10.1016/0009-8981(65)90127-0

1873-3492

F.B. De Jorge, J.Sampaio Goes, J.L. Guedes, A.B. de Ulhoa Cintra,

Radiopharmaceutical Chemistry and Applications

The authors have determined copper, copper oxidase, magnesium, inorganic sulfur, calcium and inorganic phosphorus contents in the blood serum of 23 women with carcinoma of the breast, as well as copper, magnesium, calcium and phosphorus in the mammary tissues, with normal and cancerous histopathologic diagnosis. The mean values in the blood serum were: copper 228.8 μg/100 ml ± 33.7 instead of the normal value 108.1 μg/100 ml ± 9.7; inorganic sulfur 2.264 mg/100 ml ± 0.243 instead of the normal value 1.222 mg/100 ml ± 0.193; magnesium 2.186 mequiv/l ± 0.179 instead of the normal value 2.087 mequiv/l ± 0.067; copper oxidase, calcium and inorganic phosphorus concentrations fell in the normal range. The mean values in mammary tissues were: copper 761.2 μg/100 g ± 78.3 instead of the normal value 64.9 μg/100 g ± 11.1; phosphorus 50.6 mg/100 g ± 8.7 instead of the normal value 23.5 mg/100 g ± 3.3; magnesium and calcium contents within the normal values. The results suggest that the copper content increases before phosphorus in the cancerous tissue.