Giant magnetoresistance monitoring of magnetic picodroplets in an integrated microfluidic system
2004; American Institute of Physics; Volume: 85; Issue: 20 Linguagem: Inglês
10.1063/1.1825059
ISSN1520-8842
AutoresNikola Pekas, Marc D. Porter, Mark Tondra, Anthony Popple, Albrecht Jander,
Tópico(s)Microfluidic and Capillary Electrophoresis Applications
ResumoThis letter describes the integration of giant magnetoresistance (GMR) sensors with a microfluidic system for the velocity and size monitoring, and enumeration of flowing magnetic entities. We have fabricated a microdevice that enables: (1) controlled formation of picoliter-sized droplets of a ferrofluid separated by a nonmagnetic oil; and (2) continuous-flow sensing of these ferrofluid droplets. It is shown that the flow velocity, droplet size, and droplet-formation frequency can readily be determined from the GMR response. These results are validated by comparisons to fluorescence microscopy data.
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