Correlation Between Regional Cerebral Blood Flow and Oxidative Metabolism
1976; American Medical Association; Volume: 33; Issue: 8 Linguagem: Inglês
10.1001/archneur.1976.00500080001001
ISSN1538-3687
Autores Tópico(s)S100 Proteins and Annexins
Resumo• To test the hypothesis that regional cerebral blood flow (rCBF) is normally regulated by regional metabolic activity, rCBF and the regional cerebral metabolic rate for oxygen (rCMRO 2 ) were compared in selected human subjects. In normal subjects and patients with chronic, stable diseases of brain, rCBF correlated well with rCMRO 2 . In one individual with mild dementia, rCBF and rCMRO 2 were measured before and during exercise of the hand and forearm contralateral to the hemisphere studied. Appropriate parallel changes occurred in both rCBF and rCMRO 2 during hand exercise. In patients with acute diseases affecting the hemisphere studied, however, the correlation between rCBF and rCMRO 2 was unpredictable.
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