Potential Involvement of Anxiety in the Neurobiology of Cocainea
1992; Wiley; Volume: 654; Issue: 1 Linguagem: Inglês
10.1111/j.1749-6632.1992.tb25981.x
ISSN1749-6632
Autores Tópico(s)Memory and Neural Mechanisms
ResumoAnnals of the New York Academy of SciencesVolume 654, Issue 1 p. 357-367 Potential Involvement of Anxiety in the Neurobiology of Cocainea NICK E. GOEDERS, Corresponding Author NICK E. GOEDERS Departments of Pharmacology & Therapeutics and Psychiatry Louisiana State University Medical Center Shreveport, Louisiana 71130Address correspondence to Dr. Goeders at the Department of Pharmacology & Therapeutics, P.O. Box 33932; Tel.: (318) 674-7863; Fax: (318) 674-7857.Search for more papers by this author NICK E. GOEDERS, Corresponding Author NICK E. GOEDERS Departments of Pharmacology & Therapeutics and Psychiatry Louisiana State University Medical Center Shreveport, Louisiana 71130Address correspondence to Dr. Goeders at the Department of Pharmacology & Therapeutics, P.O. Box 33932; Tel.: (318) 674-7863; Fax: (318) 674-7857.Search for more papers by this author First published: June 1992 https://doi.org/10.1111/j.1749-6632.1992.tb25981.xCitations: 7 a This work was supported by USPHS Grants DAO4293 and DAO6013 from the National Institute on Drug Abuse. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Gawin, F. H. & E. H. Ellinwood. 1988. Cocaine and other stimulants: Actions, abuse, and treatment. New Engl. J. Med. 318: 1173–1182. 2 Gawin, F. H. & E. H. Ellinwood. 1989. Cocaine dependence. Ann. Rev. Med. 40: 149–161. 3 Cohen, S. 1975. Cocaine. J. Am. Med. Assoc. 231: 74–75. 4 Resnick, R. B., R. S. Kestenbaum & L. K. Schwartz. 1977. Acute systemic effects of cocaine in man: A controlled study of intranasal and intravenous routes of administration. In Cocaine and Other Stimulants. E. H. Ellinwood & M. M. Kilbey, Eds.: 615–628. Plenum Press. New York . 5 Anthony, J. C., A. Y. Tien & K. R. Petronis. 1989. Epidemiologic evidence on cocaine use and panic attacks. Am. J. Epidemiol. 129: 543–549. 6 Aronson, T. A. & T. J. Craig. 1986. Cocaine precipitation of panic disorder. Am. J. Psychiatry 143: 643–645. 7 Washton, A. M. & M. S. Gold. 1984. Chronic cocaine abuse: Evidence for adverse effects on health and functioning. Psychiatric Ann. 14: 733–739. 8 Gay, G. R. 1981. You've come a long way baby! Coke time for the new American Lady of the eighties. J. Psychoactive Drugs 13: 297–318. 9 Tarr, J. E. & M. Macklin. 1987. Cocaine. Ped. Clin. N. Am. 34: 319–331. 10 Crowley, T. J. 1987. Clinical issues in cocaine abuse. In Cocaine: Clinical and Biobehavioral Aspects. S. Fisher, A. Raskin & E. H. Uhlenhuth, Eds.: 193–211. Oxford University Press. New York . 11 Wesson, D. R. & D. E. Smith. 1985. Cocaine: Treatment perspectives. In Cocaine Use in America: Epidemiologic and Clinical Perspectives. N. J. Kozel & N. J. Adams, Eds.: 193–202. NIDA Research Monograph 61, DHHS publication number (ADM) 85-1414. U.S. Government Printing Office. Washington , D.C . 12 Gold, P. W., G. Chrousos, C. Kellner, R. Post, A. Roy, P. Augerino, H. Schulte, E. Oldfield & D. L. Loriaux. 1984. Psychiatric implications of basic and clinical studies with corticotropin-releasing factor. Am. J. Psychiatry 141: 619–627. 13 Nemeroff, C. B. 1988. The role of corticotropin-releasing factor in the pathogenesis of major depression. Pharmacopsychiatry 21: 76–82. 14 Koob, G. F. 1985. Stress, corticotropin-releasing factor, and behavior. Perspect. Behav. Med. 2: 39–52. 15 Britton, K. T., J. Morgan, J. Rivier, W. Vale & G. F. Koob. 1985. Chlordiazepoxide attenuates response suppression induced by corticotropin-releasing factor in the conflict test. Psychopharmacology 86: 170–174. 16 Britton, K. T., G. Lee & G. F. Koob. 1988. Corticotropin-releasing factor and amphetamine exaggerate partial agonist properties of benzodiazepine Ro 15-1788 in the conflict test. Psychopharmacology 94: 306–311. 17 Swerdlow, N. R., M. A. Geyer, W. W. Vale & G. F. Koob. 1986. Corticotropin-releasing factor potentiates acoustic startle in rats: Blockade by chlordiazepoxide. Psychopharmacology 88: 147–152. 18 Forman, L. J. & S. Estilow. 1988. Cocaine influences beta-endorphin levels and release. Life Sci. 43: 309–315. 19 Moldow, R. L. & A. J. Fischman. 1987. Cocaine induced secretion of ACTH, beta-endorphin, and corticosterone. Peptides 8: 819–822. 20 Rivier, C. & W. Vale. 1987. Cocaine stimulates adrenocorticotropin (ACTH) secretion through a corticotropin-releasing factor (CRF)-mediated mechanism. Brain Res. 422: 403–406. 21 Calogero, A. E., W. T. Gallucci, M. A. Kling, G. P. Chrousos & P. W. Gold. 1989. Cocaine stimulates rat hypothalamic corticotropin-releasing hormone secretion in vitro. Brain Res. 505: 7–11. 22 Goeders, N. E., O. J. Bienvenu & E. B. De Souza. 1990. Chronic cocaine administration alters corticotropin-releasing factor receptors in the rat brain. Brain Res. 531: 322–328. 23 Goeders, N., V. Bell, A. Guidroz & M. McNulty. 1990. Dopaminergic involvement in the cocaine-induced up-regulation of benzodiazepine receptors in the rat caudate nucleus. Brain Res. 515: 1–8. 24 Onn, S., T. W. Berger, E. M. Stricker & M. J. Zigmond. 1986. Effects of intraventricular 6-hydroxydopamine on the dopaminergic innervation of striatum: Histochemical and neurochemical analysis. Brain Res. 376: 8–19. 25 De Souza, E. B., M. H. Perrin, T. R. Insel, J. Rivier, W. W. Vale & M. J. Kuhar. 1984. Corticotropin-releasing factor receptors in rat forebrain: Autoradiographic identification. Science 224: 1449–1451. 26 De Souza, E. B., T. R. Insel, M. H. Perrin, J. Rivier, W. W. Vale & M. J. Kuhar. 1985. Corticotropin-releasing factor receptors are widely distributed within the rat central nervous system: An autoradiographic study. J. Neurosci. 5: 3189–3203. 27 Javitch, J. A., S. M. Strittmatter & S. H. Snyder. 1985. Differential visualization of dopamine and norepinephrine uptake sites in rat brain using [3H]mazindol autoradiography. J. Neurosci. 5: 1513–1521. 28 Goeders, N. E. 1991. Cocaine differentially affects benzodiazepine receptors in discrete regions of the rat brain: Persistence and potential mechanisms mediating these effects. J. Pharmacol. Exp. Ther. 259: 574–581. 29 Young, W. S. III & M. J. Kuhar. 1979. A new method for receptor autoradiography: [3H]Opioid receptors in rat brain. Brain Res. 179: 255–270. 30 YOUNG, W. S. III, D. L. Niehoff, M. J. Kuhar, B. Beer & A. S. Lippa. 1981. Multiple benzodiazepine receptor localization by light microscopic radiohistochemistry. J. Pharmacol. Exp. Ther. 216: 425–430. 31 Goeders, N. E. & M. J. Kuhar. 1985. Benzodiazepine receptor binding in vivo with [3H]-Ro 15-1788. Life Sci. 37: 345–355. 32 Goeders, N. E. 1990. The effects of chronic cocaine administration on brain neurotransmitter receptors. Drug Dev. Res. 20: 349–357. 33 Goeders, N. E., M. A. McNulty, S. Mirkis & K. H. McAllister. 1989. Chlordiazepoxide alters intravenous cocaine self-administration in rats. Pharmacol. Biochem. Behav. 33: 859–866. 34 Goeders, N. E., M. A. McNulty & G. F. Guerin. 1991. Effects of alprazolam on intravenous cocaine self-administration in rats. Neurosci. Abstr. 17: 1426. 35 Chouinard, G., L. Annable, R. Fontaine & L. Solyom. 1982. Alprazolam in the treatment of generalized anxiety and panic disorders: A double-blind placebo-controlled study. Psychopharmacology 77: 229–233. 36 Dawson, G. W., S. G. Jue & R. N. Brogden. 1984. Alprazolam. A review of its pharmacodynamic properties and efficacy in the treatment of anxiety and depression. Drugs 27: 132–147. 37 Feighner, J. P., G. C. Aden, L. F. Fabre, K. Rickels & W. T. Smith. 1983. Comparison of alprazolam, imipramine and placebo in the treatment of depression. J. Am. Med. Assoc. 249: 3057–3064. 38 Rickels, K., J. P. Feighner & W. T. Smith. 1985. Alprazolam, amitriptyline, doxepin and placebo in the treatment of depression. Arch. Gen. Psychiatry 42: 134–141. 39 Church, W. H., J. B. Justice, Jr. & J. B. Byrd. 1987. Extracellular dopamine in rat striatum following uptake inhibition by cocaine, nomifensine and benztropine. Eur. J. Pharmacol. 139: 345–348. 40 Bradberry, C. W. & R. H. Roth. 1989. Cocaine increases extracellular dopamine in rat nucleus accumbens and ventral tegmental area as shown by in vivo dialysis. Neurosci. Lett. 103: 97–102. 41 Pettit, H. O. & J. B. Justice, Jr. 1989. Dopamine in the nucleus accumbens during cocaine self-administration as studied by in vivo microdialysis. Pharmacol. Biochem. Behav. 34: 899–904. 42 Kalivas, P. W. & P. Duffy. 1990. Effect of acute and daily cocaine treatment on extracellular dopamine in the nucleus accumbens. Synapse 5: 48–58. 43 Ritz, M. C., R. J. Lamb, S. R. Goldberg & M. J. Kuhar. 1987. Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science 237: 1219–1223. 44 Fischman, M. W. 1987. Cocaine and the amphetamines. In Psychopharmacology: The Third Generation of Progress. H. Y. Meltzer, Ed.: 1543–1553. Raven Press. New York . 45 Johanson, C. E. 1984. Assessment of the dependence potential of cocaine in animals. In Cocaine: Pharmacology, Effects and Treatment of Abuse. J. Grabowski, Ed.: 54–71. NIDA Research Monograph 50, DHHS publication number (ADM)84-1326. U. S. Government Printing Office. Washington , D.C. . 46 Woods, J. H., G. D. Winger & C. P. France. 1987. Reinforcing and discriminative stimulus effects of cocaine: Analysis of pharmacological mechanisms. In Cocaine: Clinical and Biobehavioral Aspects. S. Fisher, A. Raskin & E. H. Uhlenhuth, Eds.: 21–65. Oxford University Press. New York . 47 Bergman, J., B. K. Madras, S. E. Johnson & R. D. Spealman. 1989. Effects of cocaine and related drugs in nonhuman primates. III. Self-administration by squirrel monkeys. J. Pharmacol. Exp. Ther. 251: 150–155. 48 Roberts, D. C. S., M. E. Corcoran & H. C. Fibiger. 1977. On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine. Pharmacol. Biochem. Behav. 6: 615–620. 49 Roberts, D. C. S., G. F. Koob, P. Klonoff & H. C. Fibiger. 1980. Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens. Pharmacol. Biochem. Behav. 12: 781–787. 50 Roberts, D. C. S. & G. F. Koob. 1982. Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats. Pharmacol. Biochem. Behav. 17: 901–904. 51 Pettit, H. O., A. Ettenberg, F. E. Bloom & G. F. Koob. 1984. Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats. Psychopharmacology 84: 167–173. 52 Pettit, H. O., H. Pan, L. H. Parsons & J. B. Justice, Jr. 1990. Extracellular concentrations of cocaine and dopamine are enhanced during chronic cocaine administration. J. Neurochem. 55: 798–804. 53 Pettit, H. O. & J. B. Justice, Jr. 1991. Effect of dose on cocaine self-administration behavior and dopamine levels in the nucleus accumbens. Brain Res. 539: 94–102. 54 Goeders, N. E. & J. E. Smith. 1983. Cortical dopaminergic involvement in cocaine reinforcement. Science 221: 773–775. 55 Goeders, N. E. & J. E. Smith. 1986. Reinforcing properties of cocaine in the medial prefrontal cortex: Primary action on presynaptic dopaminergic terminals. Pharmacol. Biochem. Behav. 25: 191–199. 56 Goeders, N. E., S. I. Dworkin & J. E. Smith. 1986. Neuropharmacological assessment of cocaine self-administration into the medial prefrontal cortex. Pharmacol. Biochem. Behav. 24: 1429–1440. 57 Schenk, S., B. A. Horger, R. Peltier & K. Shelton. 1991. Supersensitivity to the re-inforcing effects of cocaine following 6-hydroxydopamine lesions to the medial prefrontal cortex in rats. Brain Res. 543: 227–235. 58 Goeders, N. E., G. F. Guerin, M. A. McNulty, A. M. Guidroz & S. I. Dworkin. 1991. Effects of self-administered cocaine on benzodiazepine receptors in the rat brain. FASEB J. 5 (3): A1562. 59 Guerin, G. F. & N. E. Goeders. 1991. Effects of central chlordiazepoxide infusions on intravenous cocaine self-administration in rats. In Problems of Drug Dependence, 1991. U.S. Government Printing Office. Washington , D.C . In press. 60 Goeders, N. E., M. A. McNulty, A. M. Guidroz & S. I. Dworkin. 1990. Potential neurotoxic effects of self-administered cocaine on dopamine receptors. In Problems of Drug Dependence, 1989. L. S. Harris, Ed.: 504–505. NIDA Research Monograph 95, DHHS publication number (ADM) 90-1663. U. S. Government Printing Office. Washington , D.C . 61 Goeders, N. E., G. F. Guerin, X. M. Yang & A. J. Dunn. 1990. Anxiety or stress due to cocaine. Neurosci. Abstr. 16: 581. 62 Takahashi, L. K., N. H. Kalin, J. A. Vanden Burgt & J. E. Sherman. 1989. Corticotropin-releasing factor modulates defensive-withdrawal and exploratory behavior in rats. Behav. Neurosci. 103: 648–654. 63 Butler, P. D., J. M. Weiss, J. C. Stout & C. B. Nemeroff. 1990. Corticotropin-releasing factor produces fear-enhancing and behavioral activating effects following infusion into the locus ceruleus. J. Neurosci. 10: 176–183. 64 Yang, X. M., A. L. Gorman & A. J. Dunn. 1990. The involvement of central noradrenergic systems and corticotropin-releasing factor in defensive-withdrawal behavior in rats. J. Pharmacol. Exp. Ther. 255: 1064–1070. 65 Gorman, A. L., X. M. Yang, A. J. Dunn & N. E. Goeders. 1991. Anxiogenic effects of cocaine. Neurosci. Abstr. 17: 1426. 66 Shearman, G. T. & H. Lal. 1981. Discriminative stimulus properties of cocaine related to an anxiogenic action. Prog. Neuro-Psychopharmacol. 5: 57–63. 67 Wood, D. M. & H. Lal. 1987. Anxiogenic properties of cocaine withdrawal. Life Sci. 41: 1431–1436. 68 Wood, D. M., P. R. Laraby & H. Lal. 1989. A pentylenetetrazol-like stimulus during cocaine withdrawal: Blockade by diazepam but not haloperidol. Drug Dev. Res. 16: 269–276. 69 Costall, B., M. E. Kelly, R. J. Naylor & E. S. Onaivi. 1989. The actions of nicotine and cocaine in a mouse model of anxiety. Pharmacol. Biochem. Behav. 33: 197–203. 70 Fontana, D. J. & R. L. Commissaris. 1989. Effects of cocaine on conflict behavior in the rat. Life Sci. 45: 819–827. 71 Ettenberg, A. & T. D. Geist. 1991. Animal model for investigating the anxiogenic effects of self-administered cocaine. Psychopharmacol. 103: 455–461. 72 Thierry, A. M., J. P. Tassin, G. Blanc & J. Glowinski. 1976. Selective activation of the mesocortical dopaminergic system by stress. Nature (London) 263: 242–244. 73 D'Angio, M., A. Serrano, P. Driscoll & B. Scatton. 1988. Stressful environmental stimuli increase extracellular DOPAC levels in the prefrontal cortex of hypoemotional (Roman high-avoidance) but not hyperemotional (Roman low-avoidance) rats. An in vivo voltammetric study. Brain Res. 451: 237–247. 74 Deutch, A. Y., S. Y. Tam & R. H. Roth. 1985. Footshock and conditioned stress increase 3,4-dihydroxyphenylacetic acid (DOPAC) in the ventral tegmental area but not substantia nigra. Brain Res. 333: 143–146. 75 Deutch, A. Y., W. A. Clark & R. H. Roth. 1990. Prefrontal cortical dopamine depletion enhances the responsiveness of mesolimbic dopamine neurons to stress. Brain Res. 521: 311–315. 76 Fadda, F., A. Argiolas, M. R. Melis, A. H. Tissari, P. C. Onali & G. L. Gessa. 1978. Stress-induced increase in 3,4-dihydroxyphenylacetic acid (DOPAC) levels in the cerebral cortex and in nucleus accumbens: Reversal by diazepam. Life Sci. 23: 2219–2224. 77 Lavielle, S., J. P. Tassin, A. M. Thierry, G. Blanc, D. HervÉ, C. BerthÉLÉMY & J. Glowinski. 1978. Blockade by benzodiazepines of the selective high increase in dopamine turnover induced by stress in mesocortical dopaminergic neurons of the rat. Brain Res. 168: 585–594. 78 Reinhard, J. R., Jr., M. J. Bannon & R. H. Roth. 1982. Acceleration by stress of dopamine synthesis and metabolism in prefrontal cortex: Antagonism by diazepam. Naunyn Schmiedeberg's Arch. Pharmacol. 308: 374–377. 79 Kalivas, P. W., P. Duffy & H. Eberhardt. 1990. Modulation of A10 dopamine neurons by γ-aminobutyric acid agonists. J. Pharmacol. Exp. Ther. 253: 858–866. 80 Abercrombie, E. D., K. A. Keefe, D. S. DiFrischia & M. J. Zigmond. 1989. Differential effect of stress on in vivo dopamine release in striatum, nucleus accumbens, and medial prefrontal cortex. J. Neurochem. 52: 1655–1658. 81 Kalivas, P. W. & P. Duffy. 1989. Similar effects of daily cocaine and stress on mesocorticolimbic dopamine neurotransmission in the rat. Biol. Psychiatry 25: 913–928. 82 Tam, S. Y. & R. H. Roth. 1989. Modulation of mesoprefrontal dopamine neurons by central benzodiazepine receptors. I. Pharmacological characterization. J. Pharmacol. Exp. Ther. 252: 989–996. 83 Piazza, P. V., J. M. DeminiÈRE, M. Le Moal & H. Simon. 1989. Factors that predict individual vulnerability to amphetamine self-administration. Science 245: 1511–1513. 84 Piazza, P. V., J. M. DeminiÈRE, S. Maccari, P. MormÈDE, M. Le Moal & H. Simon. 1990. Individual reactivity to novelty predicts probability of amphetamine self-administration. Behav. Pharmacol. 1: 339–345. 85 Maccari, S., P. V. Piazza, J. M. DeminiÈRE, V. Lemaire, P. MormÈDE, H. Simon, L. Angelucci & M. Le Moal 1991. Life events-induced decrease of corticosteroid type I receptors is associated with reduced corticosterone feedback and enhanced vulnerability to amphetamine self-administration. Brain Res. 547: 7–12. 86 Piazza, P. V., S. Maccari, J. M. DeminiÈRE, M. Le Moal, P. MormÈDE & H. Simon. 1991. Corticosterone levels determine individual vulnerability to amphetamine self-administration. Proc. Natl. Acad. Sci. USA 88: 2088–2092. 87 Siegel, R. K. 1984. Changing patterns of cocaine use: Longitudinal observations, consequences, and treatment. In Cocaine: Pharmacology, Effects and Treatment of Abuse. J. Grabowski, Ed.: 92–110. NIDA Research Monograph 50, DHHS publication number (ADM) 84–1326. U.S. Government Printing Office. Washington , D.C . 88 Kleber, H. D. & F. H. Gawin. 1984. Cocaine abuse: A review of current and experimental treatments. In Cocaine: Pharmacology, Effects and Treatment of Abuse. J. Grabowski, Ed.: 111–129. NIDA Research Monograph 50, DHHS publication number (ADM) 84–1326. U.S. Government Printing Office. Washington , D.C . 89 Khantzian, E. J. 1985. The self-medication hypothesis of affective disorders: Focus on heroin and cocaine dependence. Am. J. Psychiatry 142: 1259–1264. 90 Gawin, F. H. 1986. New uses of antidepressants in cocaine abuse. Psychosomatics 27: 24–29. Citing Literature Volume654, Issue1The Neurobiology of Drug and Alcohol AddictionJune 1992Pages 357-367 ReferencesRelatedInformation
Referência(s)