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Inter‐ethnic comparisons of the pharmacokinetics of the HMG‐CoA reductase inhibitor cerivastatin

1998; Wiley; Volume: 45; Issue: 6 Linguagem: Inglês

10.1046/j.1365-2125.1998.00717.x

1365-2125

Wolfgang Mück, S. Unger, K Kawano, G. Ahr,

Inflammatory mediators and NSAID effects

During the world-wide clinical development of the HMG-CoA reductase inhibitor cerivastatin, pharmacokinetic data have been collected from studies performed in Europe, North America and Japan, covering different ethnic groups, mainly Caucasians and Japanese subjects, but also Black and Hispanics. The aim of the present investigation was to search for any inter-ethnic differences in cerivastatin pharmacokinetics.