Costs of resistance: a test using transgenic Arabidopsis thaliana
1996; Royal Society; Volume: 263; Issue: 1377 Linguagem: Inglês
10.1098/rspb.1996.0242
ISSN1471-2954
AutoresJoy Bergelson, Colin B. Purrington, Curtis Palm, Juan C. López‐Gutiérrez,
Tópico(s)Plant tissue culture and regeneration
ResumoRestricted accessMoreSectionsView PDF ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InRedditEmail Cite this article Bergelson Joy , Purrington Colin B. , Palm Curtis J. and López-Gutiérrez Juan-carlos 1996Costs of resistance: a test using transgenic Arabidopsis thalianaProc. R. Soc. Lond. B.2631659–1663http://doi.org/10.1098/rspb.1996.0242SectionRestricted accessArticleCosts of resistance: a test using transgenic Arabidopsis thaliana Joy Bergelson Google Scholar Find this author on PubMed Search for more papers by this author , Colin B. Purrington Google Scholar Find this author on PubMed Search for more papers by this author , Curtis J. Palm Google Scholar Find this author on PubMed Search for more papers by this author and Juan-carlos López-Gutiérrez Google Scholar Find this author on PubMed Search for more papers by this author Joy Bergelson Google Scholar Find this author on PubMed , Colin B. Purrington Google Scholar Find this author on PubMed , Curtis J. Palm Google Scholar Find this author on PubMed and Juan-carlos López-Gutiérrez Google Scholar Find this author on PubMed Published:22 December 1996https://doi.org/10.1098/rspb.1996.0242AbstractEvolutionary biologists have long attributed polymorphisms in resistance status to fitness costs of resistance traits. Nevertheless, pleiotropic fitness costs of resistance have been notoriously difficult to detect. We have transformed Arabidopsis thaliana with a mutant acetolactate synthase gene that confers resistance to the herbicide, chlorsulfuron. Our experiment revealed a 34% reduction in the lifetime seed production of transgenic, herbicide resistant Arabidopsis thaliana relative to their susceptible null-segregants. Our experimental design allows us to conclude that this fitness cost of resistance is caused by the pleiotropic effect of the introduced acetolactate synthase gene rather than other potential costs associated with the plasmid or mutational changes induced by plant transformation. In addition, we can attribute the cost of resistance to the presence of the resistance gene rather than an increase in gene dosage. The implications of these results for the risk assessment of transgenic crops are discussed.FootnotesThis text was harvested from a scanned image of the original document using optical character recognition (OCR) software. As such, it may contain errors. Please contact the Royal Society if you find an error you would like to see corrected. Mathematical notations produced through Infty OCR. 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This Issue22 December 1996Volume 263Issue 1377 Article InformationDOI:https://doi.org/10.1098/rspb.1996.0242PubMed:9025313Published by:Royal SocietyPrint ISSN:0962-8452Online ISSN:1471-2954History: Manuscript received19/08/1996Manuscript accepted17/09/1996Published online01/01/1997Published in print22/12/1996 License:Scanned images copyright © 2017, Royal Society Citations and impact Large datasets are available through Proceedings B's partnership with Dryad
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