Epidemiology of prostatic cancer in blacks
1980; Elsevier BV; Volume: 9; Issue: 5 Linguagem: Inglês
10.1016/0091-7435(80)90035-3
ISSN1096-0260
AutoresLeonard M. Schuman, JS Mandel,
Tópico(s)Prostate Cancer Diagnosis and Treatment
ResumoAbstract Black prostatic cancer incidence and mortality rates have increased significantly in the past 50 years and, since 1945, these rates have exceeded those in whites with the black/white ratios continuing to increase significantly. A cohort effect for blacks has been noted with a leveling off since 1950 of the age-specific mortality rates for those under 65 years of age, suggesting an “environmental” factor in prostatic cancer etiology. Few urban/rural differences, if any, in mortality rates have been noted. Although the association of prostatic status and educational attainment is tenuous for whites, no comparable data for blacks have been noted. Because little is known about the occupational and other environmental exposures associated with prostatic cancer among blacks and the relationship of benign prostatic hypertrophy (BHP) to prostatic cancer remains debatable, the significance of higher rates of BHP among blacks remains unclear. Epidemiologic studies of etiologic hypotheses among whites are few in number and virtually nonexistent for blacks, particularly with respect to black/white contrasts in the same geographic settings. Some evidence for sexual and venereal hypotheses exist, but evidence for hormonal and dietary hypotheses seems more compelling. Research in these areas is highly warranted.
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