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Seroepidemiologic Study of Adult T‐Cell Leukemia Virus (ATLV) and Hepatitis B Virus Infection in Okinawa, Japan

1988; Wiley; Volume: 32; Issue: 9 Linguagem: Inglês

10.1111/j.1348-0421.1988.tb01453.x

1348-0421

Seizaburo Kashiwagi, Hideyuki Ikematsu, Jun Hayashi, Wataru Kajiyama, Hideyuki Nomura, Akinori Noguchi, Shunichi Tani, Masashi Goto,

Animal Disease Management and Epidemiology

A total of 2,283 serum samples were collected from healthy subjects in three islands of the Yaeyama district of Okinawa, Japan. These sera were tested for the presence of hepatitis B surface antigen (HBsAg), for antibody to hepatitis B core antigen (anti-HBc), and for antibody to adult T-cell leukemia-associated antigen (anti-ATLA). Correlation between hepatitis B virus infection and adult T-cell leukemia virus (ATLV) infection was determined by using the prevalence rates for three virus markers. Overall prevalence of HBsAg, anti-HBc and anti-ATLA was 6.5%, 57.4%, and 17.9%, respectively. Age-specific prevalence of anti-HBc and anti-ATLA increased with age, but that of HBsAg did not. Sex-specific prevalence of HBsAg was significantly higher in males than in females, but that of anti-ATLA was significantly higher in females than in males. Statistical analysis revealed that prevalence of anti-ATLA was significantly higher in HBsAg-positive persons and HBsAg-negative/anti-HBc-positive persons than in those negative for HBsAg and anti-HBc. These data suggest that hepatitis B virus-infected persons have a significantly higher chance of adult T-cell leukemia virus infection than those without hepatitis B virus infection in the area studied.