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Die kooperative Ewing-Sarkom-Studie CESS 81 der GPO - Analyse nach 4 Jahren* +( *

1985; Thieme Medical Publishers (Germany); Volume: 197; Issue: 03 Linguagem: Inglês

10.1055/s-2008-1033973

1439-3824

H. Jürgens, Verena Göbel, J. Michaelis, W. Ramach, J. Ritter, Rolf Sauer, J. Treuner, Voûte Pa, K. Winkler, U. Göbel,

Management of metastatic bone disease

In 1981 the cooperative Ewing's sarcoma study CESS 81 was initiated with initial 18-weeks-chemotherapy consisting of vincristine, actinomycin D, cyclophosphamide and adriamycin (VACA) followed by local therapy consisting of either radical surgery with complete resection of the involved bone or incomplete resection followed by radiation with 36 gy or radiotherapy only. Patients with radiation only for local therapy and extremity tumor sites are randomised for 46 gy vs 60 gy tumor dose. Following local therapy chemotherapy is continued for an additional 18 weeks.