Hochdosiertes Vitamin E bei chronischer Polyarthritis
1990; Thieme Medical Publishers (Germany); Volume: 15; Issue: 06 Linguagem: Inglês
10.1055/s-2008-1047457
ISSN1438-9940
AutoresG Kolarz, O Scherak, M. El Shohoumi, G. Blankenhorn,
Tópico(s)Hematological disorders and diagnostics
ResumoTo investigate whether high dose vitamin E is effective in rheumatoid arthritis, a randomized double blind study with 41 patients was performed, receiving daily doses of 3 times 544 I.U. vitamin E or 3 times 50mg Diclofenac sodium respectively for 3 weeks. With respect to clinical (morning stiffness, Ritchie's Index, overall assessment) and laboratory data, statistical examination showed no difference between both treatment regimes, responder rates being at 81% with vitamin E and at 75% with diclofenac-Na. Simultaneously measured vitamin E levels showed a clear increase of vitamin E in 55 % of the D-Alpha-Tocopherol-acetate treatment group; furthermore pain (VAS) was significantly correlated with Alpha-Tocopherol increase in the vitamin E-group.
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