LOCAL ANESTHESIA FOR PROSTATE BIOPSY BY PERIPROSTATIC LIDOCAINE INJECTION: A DOUBLE-BLIND PLACEBO CONTROLLED STUDY
2002; Lippincott Williams & Wilkins; Volume: 167; Issue: 2 Part 1 Linguagem: Inglês
10.1016/s0022-5347(01)69086-4
ISSN1527-3792
AutoresDan Leibovici, Amnon Zisman, Yoram I. Siegel, Avishay Sella, Judy Kleinmann, Arie Lindner,
Tópico(s)Body Contouring and Surgery
ResumoNo AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Feb 2002LOCAL ANESTHESIA FOR PROSTATE BIOPSY BY PERIPROSTATIC LIDOCAINE INJECTION: A DOUBLE-BLIND PLACEBO CONTROLLED STUDY DAN LEIBOVICI, AMNON ZISMAN, YORAM I. SIEGEL, AVISHAY SELLA, JUDY KLEINMANN, and ARIE LINDNER DAN LEIBOVICIDAN LEIBOVICI , AMNON ZISMANAMNON ZISMAN , YORAM I. SIEGELYORAM I. SIEGEL , AVISHAY SELLAAVISHAY SELLA , JUDY KLEINMANNJUDY KLEINMANN , and ARIE LINDNERARIE LINDNER View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)69086-4AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We determined the efficacy of anesthesia for prostate biopsy by periprostatic lidocaine injection. Materials and Methods: A total of 90 consecutive patients undergoing prostate biopsies were randomized into lidocaine and placebo groups of 45 each in double-blind fashion. A 5 ml. dose of 1% lidocaine or 0.9% sodium chloride was injected via 23 gauge needles inserted through the transrectal ultrasound probe working channel and aimed at the prostatic neurovascular bundles bilaterally. Patients completed a symptom questionnaire applying a visual analog scale of 0—none to 10—maximal addressing pre-procedure anxiety, overall pain and discomfort throughout the procedure, pain during biopsy punctures and patient tolerance, as judged by the operator. Student's t test was used to analyze continuous variables and the chi-square test was applied for categorical data. Linear regression was done to determine intervariable influences. Results: The average pain level throughout the procedure was 3.06 in the lidocaine group versus 4.15 in the control group (p = 0.04), while the pain level during biopsy punctures was 1.51 versus 3.98 (p = 0.0001) and patient tolerance was 1.06 versus 1.93 (p = 0.018). The level of discomfort throughout the procedure was lower in the lidocaine group with borderline significance (4.31 versus 5.24, p = 0.077). The lidocaine and control groups were comparable regarding average patient age (65 and 66 years, respectively). Prostate volume was similar in the 2 groups (68.5 versus 63 ml.). The median number of biopsy punctures was 7 and 8, respectively. Cancer was identified in 10 patients (22.2%) per group. Conclusions: Periprostatic lidocaine injection is an effective method of anesthesia for prostate biopsy. References 1 : The impact of prostate biopsy on patients well being: a prospective study of pain, anxiety and erectile dysfunction. J Urol2001; 165: 445. Link, Google Scholar 2 : Patient tolerance of transrectal ultrasound guided biopsy of the prostate. Br J Urol1997; 79: 608. Google Scholar 3 : A randomized prospective trial of intrarectal lidocaine for pain control during transrectal prostate biopsy: the Emory University experience. 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Google Scholar From the Departments of Urology and Oncology, Assaf-Harofeh Medical Center, Zerifin, Israel© 2002 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byCantiello F, Cicione A, Autorino R, Cosentino C, Amato F and Damiano R (2018) Pelvic Plexus Block is More Effective than Periprostatic Nerve Block for Pain Control During Office Transrectal Ultrasound Guided Prostate Biopsy: A Single Center, Prospective, Randomized, Double Arm StudyJournal of Urology, VOL. 188, NO. 2, (417-422), Online publication date: 1-Aug-2012.Bingqian L, Peihuan L, Yudong W, Jinxing W and Zhiyong W (2018) Intraprostatic Local Anesthesia With Periprostatic Nerve Block for Transrectal Ultrasound Guided Prostate BiopsyJournal of Urology, VOL. 182, NO. 2, (479-484), Online publication date: 1-Aug-2009.Cam K, Sener M, Kayikci A, Akman Y and Erol A (2018) Combined Periprostatic and Intraprostatic Local Anesthesia for Prostate Biopsy: A Double-Blind, Placebo Controlled, Randomized TrialJournal of Urology, VOL. 180, NO. 1, (141-145), Online publication date: 1-Jul-2008.Lee H, Lee H, Byun S, Lee S, Hong S and Kim S (2018) Effect of Intraprostatic Local Anesthesia During Transrectal Ultrasound Guided Prostate Biopsy: Comparison of 3 Methods in a Randomized, Double-Blind, Placebo Controlled TrialJournal of Urology, VOL. 178, NO. 2, (469-472), Online publication date: 1-Aug-2007.AUTORINO R, DE SIO M, DI LORENZO G, DAMIANO R, PERDONÀ S, CINDOLO L and D'ARMIENTO M (2018) HOW TO DECREASE PAIN DURING TRANSRECTAL ULTRASOUND GUIDED PROSTATE BIOPSY: A LOOK AT THE LITERATUREJournal of Urology, VOL. 174, NO. 6, (2091-2097), Online publication date: 1-Dec-2005.MALLICK S, HUMBERT M, BRAUD F, FOFANA M and BLANCHET P (2018) Local Anesthesia Before Transrectal Ultrasound Guided Prostate Biopsy: Comparison of 2 Methods in a Prospective, Randomized Clinical TrialJournal of Urology, VOL. 171, NO. 2, (730-733), Online publication date: 1-Feb-2004.ÖBEK C, ÖZKAN B, TUNC B, CAN G, YALCIN V and SOLOK V (2018) COMPARISON OF 3 DIFFERENT METHODS OF ANESTHESIA BEFORE TRANSRECTAL PROSTATE BIOPSY: A PROSPECTIVE RANDOMIZED TRIALJournal of Urology, VOL. 172, NO. 2, (502-505), Online publication date: 1-Aug-2004.Jones J (2018) RE: NITROUS OXIDE (ENTONOX) INHALATION AND TOLERANCE OF TRANSRECTAL ULTRASOUND GUIDED PROSTATE BIOPSY: A DOUBLE-BLIND RANDOMIZED CONTROLLED STUDYJournal of Urology, VOL. 169, NO. 5, (1799-1800), Online publication date: 1-May-2003. (2018) REPLY BY AUTHORSJournal of Urology, VOL. 168, NO. 1, (120-120), Online publication date: 1-Jul-2002. Volume 167Issue 2 Part 1February 2002Page: 563-565 Advertisement Copyright & Permissions© 2002 by American Urological Association, Inc.KeywordspainquestionnairesbiopsyprostatelidocaineMetricsAuthor Information DAN LEIBOVICI More articles by this author AMNON ZISMAN More articles by this author YORAM I. SIEGEL More articles by this author AVISHAY SELLA More articles by this author JUDY KLEINMANN More articles by this author ARIE LINDNER More articles by this author Expand All Advertisement PDF downloadLoading ...
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